Cercosporamide | Tocris Bioscience 4500 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cercosporamide

catalog :

4500

quantity :

500 ug

price :

233 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Westergard T, McAvoy K, Russell K, Wen X, Pang Y, Morris B, et al. Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress. EMBO Mol Med. 2019;11: pubmed publisher

product information

brand :

Tocris

master code :

4500

SKU :

4500/500U

product name :

Cercosporamide

description :

Potent Mnk2 inhibitor

target :

Mnk Inhibitors

category :

Small Molecules

unit size :

500 ug

purity :

96%

observed molecular weight :

331.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3 (IC50 values are 11, 31 and 116 nM for Mnk2, JAK3 and Mnk1 respectively). Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro . Also inhibits Pkc1. Orally bioavailable.

catalog number base :

4500

product keywords :

antifungals Mnk2 MKNK2 MAP-kinase interacting kinases MKNK2 Jak3 inhibitors inhibits JAK Kinase Mnk 4500,

extended description :

Potent Mnk2 inhibitor

chemical name text :

(9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide

formula :

C 16 H 13 NO 7

formula text :

C16H13NO7

cas num :

131436-22-1

2020 USD :

224

2021 USD :

233 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage