A 484954 | Tocris Bioscience 4483/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A 484954

catalog :

4483/10

quantity :

10 mg (also 50 mg)

price :

269 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Hijazi M, Casado P, Akhtar N, Álvarez Teijeiro S, Rajeeve V, Cutillas P. eEF2K Activity Determines Synergy to Cotreatment of Cancer Cells With PI3K and MEK Inhibitors. Mol Cell Proteomics. 2022;21:100240 pubmed publisher
Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher

product information

brand :

Tocris

master code :

4483

SKU :

4483/10

product name :

A 484954

unit size :

10 mg (also 50 mg)

seo description :

CaM kinase III (eEF-2 kinase) inhibitor

target :

CaM Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

289.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A 484954 is an inhibitor of eukaryotic elongation factor-2 (eEF-2) kinase (IC50 = 0.28 M in enzymatic assay). Reduces eEF-2 phosphorylation with little effect on cancer cell growth.

top caption :

CaM kinase III (eEF-2 kinase) inhibitor

extended description :

CaM kinase III (eEF-2 kinase) inhibitor

chemical name text :

7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide

formula :

C13H15N5O3

formula text :

C13H15N5O3

cas num :

142557-61-7

USD :

269 USD

product details :

CaM kinase III (eEF-2 kinase) inhibitor

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage