PR 619 | Tocris Bioscience 4482 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PR 619

catalog :

4482

quantity :

10 mg (also 50 mg)

price :

96 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Saldate J, Shiau J, Cazares V, Stuenkel E. The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology. J Biol Chem. 2018;293:2232-2246 pubmed publisher

product information

brand :

Tocris

master code :

4482

SKU :

4482/10

product name :

PR 619

description :

Broad spectrum DUB inhibitor

target :

Deubiquitinating Enzyme Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

223.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and colorectal cancer cells. Stabilizes microtubule network in oligodendroglial cells.

catalog number base :

4482

product keywords :

PR619 inhibitors DUBs deubiquitinating enzymes deubiquitination proteasome inhibits broad spectrum proteases Deubiquitinating Enzymes 4482,, DUB, Deubiquitinase

extended description :

Broad spectrum DUB inhibitor

chemical name text :

2,6-Diamino-3,5-dithiocyanopyridine

formula :

C 7 H 5 N 5 S 2

formula text :

C7H5N5S2

cas num :

2645-32-1

2020 USD :

2021 USD :

96 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage