PR 619 | Tocris Bioscience 4482/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PR 619

catalog :

4482/10

quantity :

10 mg (also 50 mg)

price :

123 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Grimsey N, Narala R, Rada C, Mehta S, Stephens B, Kufareva I, et al. A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling. Cell Rep. 2018;24:3312-3323.e5 pubmed publisher
Saldate J, Shiau J, Cazares V, Stuenkel E. The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology. J Biol Chem. 2018;293:2232-2246 pubmed publisher

product information

brand :

Tocris

master code :

4482

SKU :

4482/10

product name :

PR 619

unit size :

10 mg (also 50 mg)

seo description :

Broad spectrum DUB inhibitor

target :

Deubiquitinating Enzyme Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

223.28

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PR 619 is a broad spectrum, reversible DUB inhibitor. Exhibits limited activity against other proteases. Induces accumulation of polyubiquitinated proteins, but has no direct inhibitory effect on the proteasome. Cytotoxic in HEK293T and colorectal cancer cells. Stabilizes microtubule network in oligodendroglial cells.

top caption :

Broad spectrum DUB inhibitor

extended description :

Broad spectrum DUB inhibitor

chemical name text :

2,6-Diamino-3,5-dithiocyanopyridine

formula :

C7H5N5S2

formula text :

C7H5N5S2

cas num :

2645-32-1

USD :

123 USD

product details :

Broad spectrum DUB inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage