4mu8C | Tocris Bioscience 4479 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4mu8C

catalog :

4479

quantity :

10 mg (also 50 mg)

price :

203 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Amin Wetzel N, Saunders R, Kamphuis M, Rato C, Preissler S, Harding H, et al. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response. Cell. 2017;171:1625-1637.e13 pubmed publisher
Beisel C, Ziegler S, Martrus Zapater G, Chapel A, Griesbeck M, Hildebrandt H, et al. TLR7-mediated activation of XBP1 correlates with the IFNÎ± production in humans. Cytokine. 2017;94:55-58 pubmed publisher

product information

brand :

Tocris

master code :

4479

SKU :

4479/10

product name :

4mu8C

description :

Inhibits IRE1 endoribonuclease activity

target :

IRE1 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

204.18

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective inhibitor of IRE1 ribonuclease (RNase) activity (IC50 = 60 nM). Blocks substrate access to the active site of IRE1 . Inactivates IRE1 -mediated mRNA degradation. Displays no effect on the IRE1 -related endoribonuclease RNase L.

catalog number base :

4479

product keywords :

4m8C 4mu8C 4 8C selective inhibitors inhibits ire1 rnase endoribonuclease 4u8c IRE1 4479,

extended description :

Inhibits IRE1 endoribonuclease activity

chemical name text :

7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde

formula :

C 11 H 8 O 4

formula text :

C11H8O4

cas num :

14003-96-4

2020 USD :

197

2021 USD :

203 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage