product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
GPBAR-A
catalog :
4478/10
quantity :
10 mg (also 50 mg)
price :
276 USD
more info or order :
citations: 2
Reference
van der Linden F, Mahlandt E, Arts J, Beumer J, Puschhof J, de Man S, et al. A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium. Nat Commun. 2021;12:7159 pubmed publisher
Kowal J, Haanes K, Christensen N, Novak I. Bile acid effects are mediated by ATP release and purinergic signalling in exocrine pancreatic cells. Cell Commun Signal. 2015;13:28 pubmed publisher
product information
brand :
Tocris
master code :
4478
SKU :
4478/10
product name :
GPBAR-A
unit size :
10 mg (also 50 mg)
seo description :
GPBA receptor (TGR5) agonist
target :
GPBA Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
484.37
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
GPBAR-A is a gPBA receptor agonist. Upregulates GLP-1 secretion from intestinal cultures. Increases MQAE-fluorescence suggesting a decrease in intracellular chloride concentration in gallbladder epithelial cells.
top caption :
GPBA receptor (TGR5) agonist
extended description :
GPBA receptor (TGR5) agonist
chemical name text :
4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one
formula :
C23H15F7N2O2
formula text :
C23H15F7N2O2
cas num :
877052-79-4
USD :
276 USD
product details :
GPBA receptor (TGR5) agonist
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK