EMD 281014 hydrochloride | Tocris Bioscience 4470/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

EMD 281014 hydrochloride

catalog :

4470/10

quantity :

10 mg

price :

230 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Xing L, Kalebic N, Namba T, Vaid S, Wimberger P, Huttner W. Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex. Neuron. 2020;108:1113-1129.e6 pubmed publisher
Mayer S, Chen J, Velmeshev D, Mayer A, Eze U, Bhaduri A, et al. Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex. Neuron. 2019;102:143-158.e7 pubmed publisher

product information

brand :

Tocris

master code :

4470

SKU :

4470/10

product name :

EMD 281014 hydrochloride

unit size :

10 mg

seo description :

Selective 5-HT2A antagonist

target :

5-HT2A Receptor Antagonists

category :

Small Molecules

purity :

98%

observed molecular weight :

412.89

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EMD 281014 hydrochloride is a selective 5-HT2A antagonist; displays high affinity for human 5-HT2A over 5-HT2C receptors (Ki values are 0.87 and 557 nM respectively). Exhibits low off-target activity (Ki values are 1000 and 1268 nM for human D2 receptors and IKr channels, respectively).

top caption :

Selective 5-HT2A antagonist

extended description :

Selective 5-HT2A antagonist

chemical name text :

7-[[4-[2-(4-Fluorophenyl)ethyl]-1-piperazinyl]carbonyl]-1H-indole-3-carbonitrile hydrochloride

formula :

C22H21FN4O.HCl

formula text :

C22H21FN4O.HCl

cas num :

443144-27-2

USD :

230 USD

product details :

Selective 5-HT2A antagonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage