TCS ERK 11e | Tocris Bioscience 4465 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS ERK 11e

catalog :

4465

quantity :

10 mg

price :

293 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4465

SKU :

4465/10

product name :

TCS ERK 11e

description :

Potent and selective ERK2 inhibitor

target :

ERK Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

500.35

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective extracellular signal-related kinase 2 (ERK2) inhibitor (Ki values are 2, 395, 540 and 852 nM for ERK2, GSK-3, Aurora Kinase A and Cdk2 respectively). Potently blocks proliferation of HT29 cells (IC50 = 48 nM). Orally bioavailable.

catalog number base :

4465

product keywords :

TCSERK11e extracellular signal related kinase 2 ERK2 inhibitors inhibits potent selective cell permeable orally bioavailable VTX11e VX11e VX 11e ERK 4465,

extended description :

Potent and selective ERK2 inhibitor

chemical name text :

4-[2-[(2-Chloro-4-fluorophenyl)amino]-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide

formula :

C 24 H 20 Cl 2 FN 5 O 2

formula text :

C24H20Cl2FN5O2

cas num :

896720-20-0

2020 USD :

284

2021 USD :

293 USD

alt names :

VX 11e

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage