IOX 1 | Tocris Bioscience 4464 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IOX 1

catalog :

4464

quantity :

10 mg (also 50 mg)

price :

193 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Li H, Yao Q, Mariscal A, Wu X, Hulse J, Pedersen E, et al. Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation. Nat Commun. 2018;9:1420 pubmed publisher

product information

brand :

Tocris

master code :

4464

SKU :

4464/10

product name :

IOX 1

description :

Histone demethylase inhibitor; cell permeable

target :

Histone Demethylase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

189.17

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Histone demethylase JMJD inhibitor (IC50 values are 0.12, 0.17, 0.2, 0.3, 0.6 and 1 M for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively). Cell permeable; inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa cells.

catalog number base :

4464

product keywords :

IOX1 histone demethylases inhibitors inhibits JMJD2 JMJD3 JMJD6 JMJD1 UTX H3K9me3 demethylation demethylates cell permeable in vitro activity sgc 5-carboxy-8HQ Histone Demethylases 4464,

extended description :

Histone demethylase inhibitor; cell permeable

chemical name text :

8-Hydroxy-5-quinolinecarboxylic acid

formula :

C 10 H 7 NO 3

formula text :

C10H7NO3

cas num :

5852-78-8

2020 USD :

187

2021 USD :

193 USD

alt names :

5-carboxy-8HQ

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage