chemical

TC-S 7005

4459

10 mg

301 USD

4459

4459/10

TC-S 7005

Potent and selective PLK2 inhibitor

Polo-like Kinase Inhibitors

Small Molecules

10 mg

98%

359.38

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.

4459

TC-S7005 potent selective PLK2 inhibitors inhibits PLK1 PLK3 TCS7005 mitosis PLK cell cycle kinases polo-like polo like Polo-like Kinase Mitosis 4459,

Potent and selective PLK2 inhibitor

3-(1,3-Benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-isoxazolo[5,4-c]pyridin-5-amine

C 21 H 17 N 3 O 3

C21H17N3O3

1082739-92-1

289

301 USD

Store at +4°C