TC-S 7005 | Tocris Bioscience 4459/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-S 7005

catalog :

4459/10

quantity :

10 mg

price :

337 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Arimoto K, Miyauchi S, Troutman T, Zhang Y, Liu M, Stoner S, et al. Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis. Nat Commun. 2023;14:251 pubmed publisher

product information

brand :

Tocris

master code :

4459

SKU :

4459/10

product name :

TC-S 7005

unit size :

10 mg

seo description :

Potent and selective PLK2 inhibitor

target :

Polo-like Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

359.38

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-S 7005 is a potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.

top caption :

Potent and selective PLK2 inhibitor

extended description :

Potent and selective PLK2 inhibitor

chemical name text :

3-(1,3-Benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-isoxazolo[5,4-c]pyridin-5-amine

formula :

C21H17N3O3

formula text :

C21H17N3O3

cas num :

1082739-92-1

USD :

337 USD

product details :

Potent and selective PLK2 inhibitor

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage