chemical

IOX 2

4451

10 mg (also 50 mg)

234 USD

4451

4451/10

IOX 2

Potent, selective HIF-1 prolyl hydroxylase-2 (PHD2) inhibitor

Hydroxylase Inhibitors

Small Molecules

10 mg (also 50 mg)

99%

352.34

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Potent inhibitor of HIF-1 prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.

4451

supplier IOX2 hypoxia inducible factor 1 alpha 1a HIF1a HIF1alpha prolyl hydroxylases potent inhibits inhibitors selective cell permeable epigenetics probe JICL38 sgc PHD2 Hydroxylases Hypoxia Inducible Factors 4451,

Potent, selective HIF-1 prolyl hydroxylase-2 (PHD2) inhibitor

N-[[1,2-Dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]glycine

C 19 H 16 N 2 O 5

C19H16N2O5

931398-72-0

225

234 USD

Store at +4°C