Org 24598 | Tocris Bioscience 4447/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Org 24598

catalog :

4447/10

quantity :

10 mg (also 50 mg)

price :

267 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Woo J, Jang M, Lee J, Koh W, Mikoshiba K, Lee C. The molecular mechanism of synaptic activity-induced astrocytic volume transient. J Physiol. 2020;598:4555-4572 pubmed publisher

image

image 1 :

Cat.No. 4447 - Org 24598 C19H20F3NO3 CAS No. 372198-97-5

product information

brand :

Tocris

master code :

4447

SKU :

4447/10

product name :

Org 24598

unit size :

10 mg (also 50 mg)

seo description :

Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo

target :

Glycine Transporter Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

367.36

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Org 24598 is a potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM). Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 in vivo .

top caption :

Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo

extended description :

Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo

chemical name text :

N-Methyl-N-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-glycine

formula :

C19H20F3NO3

formula text :

C19H20F3NO3

cas num :

372198-97-5

USD :

267 USD

product details :

Potent and selective inhibitor of the glial glycine transporter GlyT1b; active in vivo

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage