Fatostatin A | Tocris Bioscience 4444 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Fatostatin A

catalog :

4444

quantity :

10 mg (also 50 mg)

price :

125 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
de la Roche M, Hamilton C, Mortensen R, Jeyaprakash A, Ghosh S, Anand P. Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol. 2018;217:3560-3576 pubmed publisher

product information

brand :

Tocris

master code :

4444

SKU :

4444/10

product name :

Fatostatin A

description :

Cell permeable inhibitor of SREBP activation

target :

SREBP Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

375.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of sterol regulatory element binding protein (SREBP); impairs the activation of SREBP-1 and SREBP-2. Exhibits antiproliferative effects in DU 145 cells independently of IGF-1 signaling (IC50 = 0.1 M); reverses hyperglycemia in diabetic ( ob/ob ) mice. Cell permeable.

catalog number base :

4444

product keywords :

sterol regulatory element binding proteins SREBPs SREBP1 SREBP2 inhibition inhibitors inhibits antiproliferatives 125B11 FatostatinA SREBP 4444,

extended description :

Cell permeable inhibitor of SREBP activation

chemical name text :

4-[4-(4-Methylphenyl)-2-thiazolyl]-2-propylpyridine hydrobromide

formula :

C 18 H 18 N 2 S.HBr

formula text :

C18H18N2S.HBr

cas num :

298197-04-3

2020 USD :

120

2021 USD :

125 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage