SEN 12333 | Tocris Bioscience 4441 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SEN 12333

catalog :

4441

quantity :

10 mg (also 50 mg)

price :

130 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4441

SKU :

4441/10

product name :

SEN 12333

description :

7 nAChR agonist; also histamine H3 antagonist

target :

Nicotinic (a7) Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

339.43

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

7 nicotinic acetylcholine receptor (nAChR) agonist (EC50 = 1.6 M, Ki = 260 nM at rat 7 nAChRs). Also displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic 3 nAChRs (IC50 = 8.5 M). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. Brain penetrant and orally bioavailable.

catalog number base :

4441

product keywords :

SEN12333 WAY317538 WAY 317538 alpha7 a7 7 nicotinic acetylcholine receptors nAChR agonists histamine h3 receptors functional antagonists brain penetrant orally bioavailable WAY 317538 Nicotinic (a7) Receptors Histamine H3 Receptors 4441,

extended description :

7 nAChR agonist; also histamine H3 antagonist

chemical name text :

N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide

formula :

C 20 H 25 N 3 O 2

formula text :

C20H25N3O2

cas num :

874450-44-9

2020 USD :

162

2021 USD :

130 USD

alt names :

WAY 317538

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage