8-Chloroadenosine | Tocris Bioscience 4436/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8-Chloroadenosine

catalog :

4436/10

quantity :

10 mg (also 50 mg)

price :

275 USD

citations: 1

Reference
Kearney A, Fan Y, Giri U, Saigal B, Gandhi V, Heymach J, et al. 8-Chloroadenosine Sensitivity in Renal Cell Carcinoma Is Associated with AMPK Activation and mTOR Pathway Inhibition. PLoS ONE. 2015;10:e0135962 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4436

SKU :

4436/10

product name :

8-Chloroadenosine

description :

Cytotoxic nucleoside analog; inhibits RNA synthesis

target :

DNA, RNA and Protein Synthesis Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

301.69

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

8-Chloroadenosine is a nucleoside analog; metabolized in vivo to 8-Chloro-ATP. Incorporates into RNA during transcription and inhibits RNA synthesis. Exhibits cytotoxicity in MM.1S, RPMI-8226 and U266 cancer cell lines; induces G2/M cell cycle arrest and mitotic catastrophe in A549 and H1299 cells.

product keywords :

8-Cl-Ado 8-Cl-ATP cytotoxic chemotherapeutics growth arrest RNA synthesis transcription inhibitors inhibits nucleoside analogs DNA, RNA and Protein Synthesis Cell Cycle Inhibitors 4436,

extended description :

Cytotoxic nucleoside analog; inhibits RNA synthesis

chemical name text :

6-Amino-8-chloropurine riboside

formula :

C10H12ClN5O4

formula text :

C10H12ClN5O4

cas num :

34408-14-5

USD :

272

USD 2025 :

275 USD

product details :

Cytotoxic nucleoside analog; inhibits RNA synthesis