TC-N 1752 | Tocris Bioscience 4435 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-N 1752

catalog :

4435

quantity :

10 mg (also 50 mg)

price :

261 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Curtright A, Rosser M, Goh S, Keown B, Wagner E, Sharifi J, et al. Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery. PLoS ONE. 2015;10:e0116766 pubmed publisher

product information

brand :

Tocris

master code :

4435

SKU :

4435/10

product name :

TC-N 1752

description :

NaV channel blocker

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

516.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Human NaV channel inhibitor (IC50 values are 0.17, 0.3, 0.4, 1.1 and 1.6 M at hNaV1.7, hNaV1.3, hNaV1.4, hNaV1.5 and hNav1.9 respectively). Also inhibits tetrodotoxin-sensitive sodium channels. Displays analgesic efficacy in the formalin pain model.

catalog number base :

4435

product keywords :

TCN1752 sodium channels blockers selective nav analgesics Voltage-gated Sodium Channels 4435,

extended description :

NaV channel blocker

chemical name text :

N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide

formula :

C 25 H 27 F 3 N 6 O 3

formula text :

C25H27F3N6O3

cas num :

1211866-85-1

2020 USD :

253

2021 USD :

261 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage