TC-N 1752 | Tocris Bioscience 4435/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-N 1752

catalog :

4435/10

quantity :

10 mg (also 50 mg)

price :

329 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Li K, Abbott S, Shi Y, Eggan P, Gonye E, Bayliss D. TRPM4 mediates a subthreshold membrane potential oscillation in respiratory chemoreceptor neurons that drives pacemaker firing and breathing. Cell Rep. 2021;34:108714 pubmed publisher
Curtright A, Rosser M, Goh S, Keown B, Wagner E, Sharifi J, et al. Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery. PLoS ONE. 2015;10:e0116766 pubmed publisher

image

image 1 :

Cat.No. 4435 - TC-N 1752 C25H27F3N6O3 CAS No. 1211866-85-1

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4435

SKU :

4435/10

product name :

TC-N 1752

description :

NaV channel blocker

target :

Voltage-gated Sodium Channel Blockers

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

516.52

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-N 1752 is a human NaV channel inhibitor (IC50 values are 0.17, 0.3, 0.4, 1.1 and 1.6 M at hNaV1.7, hNaV1.3, hNaV1.4, hNaV1.5 and hNav1.9 respectively). Also inhibits tetrodotoxin -sensitive sodium channels. Displays analgesic efficacy in the formalin pain model.

product keywords :

TCN1752 sodium channels blockers selective nav analgesics Voltage-gated Sodium Channels 4435,

extended description :

NaV channel blocker

chemical name text :

N-[2-Methyl-3-[[4-[4-[[4-(trifluoromethoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triazin-2-yl]amino]phenyl]acetamide

formula :

C25H27F3N6O3

formula text :

C25H27F3N6O3

cas num :

1211866-85-1

USD :

325

USD 2025 :

329 USD

product details :

NaV channel blocker

more info or order :

Tocris Bioscience product webpage