Wiskostatin | Tocris Bioscience 4434 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Wiskostatin

catalog :

4434

quantity :

10 mg (also 50 mg)

price :

221 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rassokhin M, Pakhomov A. Cellular regulation of extension and retraction of pseudopod-like blebs produced by nanosecond pulsed electric field (nsPEF). Cell Biochem Biophys. 2014;69:555-66 pubmed publisher

product information

brand :

Tocris

master code :

4434

SKU :

4434/10

product name :

Wiskostatin

description :

N-WASP inhibitor; inhibits Arp2/3 activation

target :

Actin-related Products

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

426.15

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity. Interacts with the regulatory GTPase-binding domain of N-WASP; inhibits activation of Arp2/3 complex by maintaining N-WASP in an inactive conformation. Also inhibits PIP2-induced actin polymerization (EC50 ~ 4 M).

catalog number base :

4434

product keywords :

Arp2/3 complex n-wasp wiskott-aldrich syndrome inhibitors inhibits actin polymerization 3,6-Dibromo-a-[(dimethylamino)methyl]-9H-cabazole-9-ethanol Actin 4434,

extended description :

N-WASP inhibitor; inhibits Arp2/3 activation

chemical name text :

3,6-Dibromo- -[(dimethylamino)methyl]-9H-cabazole-9-ethanol

formula :

C 17 H 18 Br 2 N 2 O

formula text :

C17H18Br2N2O

cas num :

253449-04-6

2020 USD :

216

2021 USD :

221 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage