Wiskostatin | Tocris Bioscience 4434/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Wiskostatin

catalog :

4434/10

quantity :

10 mg (also 50 mg)

price :

278 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Endo Y, Hickerson B, Ilyushina N, Mohan N, Peng H, Takeda K, et al. Identification of a pharmacological approach to reduce ACE2 expression and development of an in vitro COVID-19 viral entry model. J Virus Erad. 2022;8:100307 pubmed publisher
Mageswaran S, Yang W, Chakrabarty Y, Oikonomou C, Jensen G. A cryo-electron tomography workflow reveals protrusion-mediated shedding on injured plasma membrane. Sci Adv. 2021;7: pubmed publisher
Rassokhin M, Pakhomov A. Cellular regulation of extension and retraction of pseudopod-like blebs produced by nanosecond pulsed electric field (nsPEF). Cell Biochem Biophys. 2014;69:555-66 pubmed publisher

image

image 1 :

Cat.No. 4434 - Wiskostatin C17H18Br2N2O CAS No. 253449-04-6

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4434

SKU :

4434/10

product name :

Wiskostatin

description :

N-WASP inhibitor; inhibits Arp2/3 activation

target :

Actin-related Products

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

426.15

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Wiskostatin is an inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity. Interacts with the regulatory GTPase-binding domain of N-WASP; inhibits activation of Arp2/3 complex by maintaining N-WASP in an inactive conformation. Also inhibits PIP2-induced actin polymerization (EC50 ~ 4 M).

product keywords :

Arp2/3 complex n-wasp wiskott-aldrich syndrome inhibitors inhibits actin polymerization 3,6-Dibromo-a-[(dimethylamino)methyl]-9H-cabazole-9-ethanol Actin 4434,

extended description :

N-WASP inhibitor; inhibits Arp2/3 activation

chemical name text :

3,6-Dibromo- -[(dimethylamino)methyl]-9H-cabazole-9-ethanol

formula :

C17H18Br2N2O

formula text :

C17H18Br2N2O

cas num :

253449-04-6

USD :

275

USD 2025 :

278 USD

product details :

N-WASP inhibitor; inhibits Arp2/3 activation

more info or order :

Tocris Bioscience product webpage