product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BAY 41-2272
catalog :
4430/10
quantity :
10 mg (also 50 mg)
price :
262 USD
more info or order :
product information
brand :
Tocris
master code :
4430
SKU :
4430/10
rank :
0.061
product name :
BAY 41-2272
description :
Soluble guanylyl cyclase (sGC) activator
target :
Guanylyl Cyclase Activators
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BAY 41-2272 is an activator of soluble guanylyl cyclase (sGC); acts at a nitric oxide (NO)-independent regulatory site in the sGC 1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 M). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.
extended description :
Soluble guanylyl cyclase (sGC) activator
chemical name text :
5-Cyclopropyl-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-pyrimidinamine
formula :
C 20 H 17 FN 6
formula text :
C20H17FN6
cas num :
256376-24-6
USD :
262 USD
product details :
Soluble guanylyl cyclase (sGC) activator
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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