MitoPY1 | Tocris Bioscience 4428 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MitoPY1

catalog :

4428

quantity :

10 mg

price :

348 USD

more info or order :

Tocris Bioscience product webpage

citations: 10

Reference
Moreira H, Szyjka A, Paliszkiewicz K, Barg E. Prooxidative Activity of Celastrol Induces Apoptosis, DNA Damage, and Cell Cycle Arrest in Drug-Resistant Human Colon Cancer Cells. Oxid Med Cell Longev. 2019;2019:6793957 pubmed publisher
Karunakaran U, Elumalai S, Moon J, Won K. CD36 dependent redoxosomes promotes ceramide-mediated pancreatic β-cell failure via p66Shc activation. Free Radic Biol Med. 2019;134:505-515 pubmed publisher
Abuaita B, Schultz T, O Riordan M. Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus. Cell Host Microbe. 2018;24:625-636.e5 pubmed publisher
Zhang Y, Lee J, Paull T, Gehrke S, D Alessandro A, Dou Q, et al. Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity. Sci Signal. 2018;11: pubmed publisher
Zlatic S, Vrailas Mortimer A, Gokhale A, Carey L, Scott E, Burch R, et al. Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees. Cell Syst. 2018;6:368-380.e6 pubmed publisher
Andrienko T, Pasdois P, Rossbach A, Halestrap A. Real-Time Fluorescence Measurements of ROS and [Ca2+] in Ischemic / Reperfused Rat Hearts: Detectable Increases Occur only after Mitochondrial Pore Opening and Are Attenuated by Ischemic Preconditioning. PLoS ONE. 2016;11:e0167300 pubmed publisher
Griffith A, Venables T, Shi J, Farr A, Van Remmen H, Szweda L, et al. Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency. Cell Rep. 2015;12:1071-9 pubmed publisher
Beyer A, Durand M, Hockenberry J, Gamblin T, Phillips S, Gutterman D. An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles. Am J Physiol Heart Circ Physiol. 2014;307:H1587-93 pubmed publisher
CamarÃ© C, Trayssac M, Garmy Susini B, Mucher E, Sabbadini R, Salvayre R, et al. Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody. Br J Pharmacol. 2015;172:106-18 pubmed publisher
Freed J, Beyer A, LoGiudice J, Hockenberry J, Gutterman D. Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation. Circ Res. 2014;115:525-32 pubmed publisher

product information

brand :

Tocris

master code :

4428

SKU :

4428/10

product name :

MitoPY1

description :

Fluorescent mitochondrial hydrogen peroxide indicator

target :

Fluorescent Cell Indicators and Sensors

category :

Small Molecules

unit size :

10 mg

observed molecular weight :

954.68

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells. Displays enhanced emission at 528 nm in the presence of H2O2. Selective for H2O2 over superoxide, nitric oxide and hydroxyl radical. Detects local increases in H2O2 in an in vitro model of Parkinson s Disease.

catalog number base :

4428

product keywords :

supplier fluorescent probes reagents imaging mitochondria living cells hydrogen peroxide H2O2 selective oxidative stress ROS reactive oxygen species Fluorescent Cell Indicators and Sensors 4428,

extended description :

Fluorescent mitochondrial hydrogen peroxide indicator

chemical name text :

[4-[4-[3-Oxo-6 -(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9 -[9H]xanthen]-3 -yl]-1-piperazinyl]butyl]triphenyl-phosphonium iodide

formula :

C 52 H 53 BIN 2 O 5 P

formula text :

C52H53BIN2O5P

cas num :

1041634-69-8

2020 USD :

331

2021 USD :

348 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage