Saquinavir mesylate | Tocris Bioscience 4418 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Saquinavir mesylate

catalog :

4418

quantity :

10 mg (also 50 mg)

price :

61 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lan J, Yang K, Byrd D, Hu N, Amet T, Shepherd N, et al. Provirus activation plus CD59 blockage triggers antibody-dependent complement-mediated lysis of latently HIV-1-infected cells. J Immunol. 2014;193:3577-89 pubmed publisher

product information

brand :

Tocris

master code :

4418

SKU :

4418/10

product name :

Saquinavir mesylate

description :

HIV protease inhibitor

target :

Additional Synthetic Protease Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

766.95

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of human immunodeficiency virus (HIV) protease (Ki values are 0.1 and 0.12 nM for HIV-2 and HIV-1 protease respectively). Exhibits high antiviral activity and low cytotoxicity. In silico docking models predict potential as an inhibitor of SARS-CoV-2 3CLpro.

catalog number base :

4418

product keywords :

hiv hiv-1 hiv-2 protease proteinase inhibitors inhibits Ro31-8959 human immunodeficiency virus antivirals SARS-Cov-2 COVID-19 coronaviruses severe acute respiratory syndrome 3CLpro Ro 31-8959 COVID-19 HIV Protease HIV 4418, HIV, human immunodeficiency virus, acquired immunodeficiency syndrome

extended description :

HIV protease inhibitor

chemical name text :

(2S)-N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate

formula :

C 38 H 50 N 6 O 5 .CH 4 O 3 S

formula text :

C38H50N6O5.CH4O3S

cas num :

149845-06-7

2020 USD :

2021 USD :

61 USD

alt names :

Ro 31-8959

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage