MK 0343 | Tocris Bioscience 4415 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MK 0343

catalog :

4415

quantity :

10 mg (also 50 mg)

price :

250 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4415

SKU :

4415/10

product name :

MK 0343

description :

GABAA partial agonist; displays subtype selectivity

target :

GABA-A Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

397.38

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Subtype-selective GABAA partial agonist (Ki values are 0.21, 0.22, 0.23 and 0.40 for 3, 1, 5 and 2 respectively); occupies the benzodiazepine site of GABAA receptors. Displays greater agonist efficacy at 3 compared to 1. Exhibits anxiolytic and non-sedating properties in rodent models. Brain penetrant.

catalog number base :

4415

product keywords :

MK0343 gabaa subtype-selective partial agonists 3 alpha3 a3 anxiolytics brain penetrant GABAA Receptors 4415,

extended description :

GABAA partial agonist; displays subtype selectivity

chemical name text :

7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazo[4,3-b]pyridazine

formula :

C 19 H 17 F 2 N 7 O

formula text :

C19H17F2N7O

cas num :

233275-76-8

2020 USD :

250

2021 USD :

250 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage