SR 1664 | Tocris Bioscience 4409 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SR 1664

catalog :

4409

quantity :

10 mg (also 50 mg)

price :

160 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4409 - SR 1664 C33H29N3O5 CAS No. 1338259-05-4

product information

brand :

Tocris

master code :

4409

SKU :

4409/10

product name :

SR 1664

description :

High affinity PPAR ligand; blocks Cdk5-dependent PPAR phosphorylation

target :

Additional PPAR gamma Receptor Products

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

547.6

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antidiabetic agent; binds to PPAR and potently inhibits Cdk5-mediated PPAR phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR agonist activity. Does not inhibit Cdk5-dependent phosphorylation of Rb. Reduces fasting insulin levels and improves insulin sensitivity in a mouse model of diabetes.

catalog number base :

4409

product keywords :

SR1664 antidiabetics diabetes PPARgamma PPARg peroxisome proliferator activated receptor ligand Cdk5 phosphorylation LBD PPARgamma Receptors 4409,

extended description :

High affinity PPAR ligand; blocks Cdk5-dependent PPAR phosphorylation

chemical name text :

4 -[[2,3-Dimethyl-5-[[[(1S)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1H-indol-1-yl]methyl]-[1,1 -biphenyl]-2-carboxylic acid

formula :

C 33 H 29 N 3 O 5

formula text :

C33H29N3O5

cas num :

1338259-05-4

2020 USD :

156

2021 USD :

160 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage