SMIFH2 | Tocris Bioscience 4401 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SMIFH2

catalog :

4401

quantity :

10 mg (also 50 mg)

price :

125 USD

more info or order :

Tocris Bioscience product webpage

citations: 9

Reference
Alieva N, Efremov A, Hu S, Oh D, Chen Z, Natarajan M, et al. Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion. Nat Commun. 2019;10:3593 pubmed publisher
Ray P, Chin A, Worley K, Fan J, Kaur G, Wu M, et al. Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping. Proc Natl Acad Sci U S A. 2018;115:E11568-E11577 pubmed publisher
Ford C, NANS A, Boucrot E, Hayward R. Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entry. PLoS Pathog. 2018;14:e1007051 pubmed publisher
LeCorgne H, Tudosie A, Lavik K, Su R, Becker K, Moore S, et al. Differential Toxicity of mDia Formin-Directed Functional Agonists and Antagonists in Developing Zebrafish. Front Pharmacol. 2018;9:340 pubmed publisher
Sepúlveda Ramírez S, Toledo Jacobo L, Henson J, Shuster C. Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo. Dev Biol. 2018;437:140-151 pubmed publisher
Logue J, Cartagena Rivera A, Chadwick R. c-Src activity is differentially required by cancer cell motility modes. Oncogene. 2018;37:2104-2121 pubmed publisher
Basu S, Kustanovich I, Lamprecht R. Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala. Eneuro. 2016;3: pubmed
Ganguly A, Tang Y, Wang L, Ladt K, Loi J, Dargent B, et al. A dynamic formin-dependent deep F-actin network in axons. J Cell Biol. 2015;210:401-17 pubmed publisher
Tornavaca O, Chia M, Dufton N, Almagro L, Conway D, Randi A, et al. ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. J Cell Biol. 2015;208:821-38 pubmed publisher

product information

brand :

Tocris

master code :

4401

SKU :

4401/10

product name :

SMIFH2

description :

FH2 domain inhibitor; prevents actin nucleation

target :

Actin-related Products

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

377.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation and barbed end elongation. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.

catalog number base :

4401

product keywords :

SMIFH2 formins homology fh2 domains inhibitors inhibits actin nucleation Actin 4401,

extended description :

FH2 domain inhibitor; prevents actin nucleation

chemical name text :

1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione

formula :

C 15 H 9 BrN 2 O 3 S

formula text :

C15H9BrN2O3S

cas num :

340316-62-3

2020 USD :

120

2021 USD :

125 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage