product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SC 66
catalog :
4398
quantity :
10 mg (also 50 mg)
price :
90 USD
more info or order :
citations: 2
Reference
Deng H, Hillpot E, Mondal S, Khurana K, Woodworth C. HPV16-Immortalized Cells from Human Transformation Zone and Endocervix are More Dysplastic than Ectocervical Cells in Organotypic Culture. Sci Rep. 2018;8:15402 pubmed publisher
Hung C, Chien C, Chiang W, Lin C, Hour T, Chen H, et al. p22phox confers resistance to cisplatin, by blocking its entry into the nucleus. Oncotarget. 2015;6:4110-25 pubmed
product information
brand :
Tocris
master code :
4398
SKU :
4398/10
product name :
SC 66
description :
Allosteric Akt inhibitor
target :
Akt (Protein Kinase B) Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
276.33
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Exhibits anticancer activity in vitro and in vivo .
catalog number base :
4398
product keywords :
SC66 akt pkb protein kinase b inhibitors inhibits allosteric dual activity inhibitory Akt (Protein Kinase B) Protein Kinase B/Akt 4398,
extended description :
Allosteric Akt inhibitor
chemical name text :
(2E,6E)-2,6-Bis(4-pyridinylmethylene)cyclohexanone
formula :
C 18 H 16 N 2 O
formula text :
C18H16N2O
cas num :
871361-88-5
2020 USD :
90
2021 USD :
90 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK