Piperlongumine | Tocris Bioscience 4396 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Piperlongumine

catalog :

4396

quantity :

10 mg (also 50 mg)

price :

183 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Farrand L, Kim J, Im aram A, Suh J, Lee H, Tsang B. An improved quantitative approach for the assessment of mitochondrial fragmentation in chemoresistant ovarian cancer cells. PLoS ONE. 2013;8:e74008 pubmed publisher

product information

brand :

Tocris

master code :

4396

SKU :

4396/10

product name :

Piperlongumine

description :

Induces apoptosis; increases p53 and ROS levels in cancer cells

target :

Apoptosis Inducer Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

317.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and normal p53. Also inhibits the growth of spontaneous malignant breast tumors in mice. Displays little effect on normal cells. Rapidly depletes androgen receptor expression in human prostate cancer cells via a ROS-dependent, proteasome-mediated mechanism.

catalog number base :

4396

product keywords :

antitumor selectively cytotoxic increases induces ros reactive oxygen species cancer cells piperlongumine supplier androgen receptor p53 proapoptotic p53 Apoptosis Inducers Androgen Receptor 4396,

extended description :

Induces apoptosis; increases p53 and ROS levels in cancer cells

chemical name text :

5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone

formula :

C 17 H 19 NO 5

formula text :

C17H19NO5

cas num :

20069-09-4

2020 USD :

179

2021 USD :

183 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage