Ro 51 | Tocris Bioscience 4391/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ro 51

catalog :

4391/10

quantity :

10 mg (also 50 mg)

price :

287 USD

citations: 1

Reference
Lu V, Rievaj J, O Flaherty E, Smith C, Pais R, Pattison L, et al. Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons. Nat Commun. 2019;10:1029 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4391

SKU :

4391/10

product name :

Ro 51

description :

Potent P2X3 and P2X2/3 antagonist

target :

P2X Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

474.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ro 51 is a potent, dual P2X3 and P2X2/3 antagonist (IC50 values are 2 and 5 nM for rP2X3 and hP2X2/3 respectively). Selective for P2X3 and P2X2/3 over other P2X receptors (IC50 values are > 10 M for P2X1, P2X2, P2X4, P2X5, and P2X7). Cell permeable.

product keywords :

Ro51 Potent selective P2X3 P2X2/3 P2X purinergic receptors antagonists purinoceptors P2X Receptors 4391,

extended description :

Potent P2X3 and P2X2/3 antagonist

chemical name text :

2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinyl]amino]-1,3-propanediol

formula :

C17H23IN4O4

formula text :

C17H23IN4O4

cas num :

1050670-85-3

USD :

284

USD 2025 :

287 USD

product details :

Potent P2X3 and P2X2/3 antagonist