Donepezil hydrochloride | Tocris Bioscience 4385 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Donepezil hydrochloride

catalog :

4385

quantity :

10 mg (also 50 mg)

price :

75 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Rennekamp A, Huang X, Wang Y, Patel S, Lorello P, Cade L, et al. ?1 receptor ligands control a switch between passive and active threat responses. Nat Chem Biol. 2016;12:552-8 pubmed publisher
Morris M, Sanchez P, Verret L, Beagle A, Guo W, Dubal D, et al. Network dysfunction in α-synuclein transgenic mice and human Lewy body dementia. Ann Clin Transl Neurol. 2015;2:1012-28 pubmed publisher

product information

brand :

Tocris

master code :

4385

SKU :

4385/10

product name :

Donepezil hydrochloride

description :

Potent AChE inhibitor

target :

Cholinesterase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

415.95

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent acetylcholinesterase inhibitor (IC50 = 5.7 nM). Displays 1252-fold selectivity for AChE over BuChE (IC50 = 7138 nM for BuChE). Orally active. . Deuterated analog also available.

catalog number base :

4385

product keywords :

acetylcholinesterase ache selective potent inhibitors inhibits E2020 E 2020 Cholinesterases 4385,

extended description :

Potent AChE inhibitor

chemical name text :

2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one hydrochloride

formula :

C 24 H 29 NO 3 .HCl

formula text :

C24H29NO3.HCl

cas num :

120011-70-3

2020 USD :

2021 USD :

75 USD

alt names :

E 2020

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage