product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Letrozole
catalog :
4382
quantity :
10 mg (also 50 mg)
price :
75 USD
more info or order :
citations: 3
Reference
Ali R, Samman N, Al Zahrani H, Nehdi A, Rahman S, Khan A, et al. Isolation and characterization of a new naturally immortalized human breast carcinoma cell line, KAIMRC1. BMC Cancer. 2017;17:803 pubmed publisher
Ruiz Palmero I, Ortiz Rodriguez A, Melcangi R, Caruso D, Garcia Segura L, Rune G, et al. Oestradiol synthesized by female neurons generates sex differences in neuritogenesis. Sci Rep. 2016;6:31891 pubmed publisher
Tozzi A, de Iure A, Tantucci M, Durante V, Quiroga Varela A, Giampà C, et al. Endogenous 17β-estradiol is required for activity-dependent long-term potentiation in the striatum: interaction with the dopaminergic system. Front Cell Neurosci. 2015;9:192 pubmed publisher
product information
brand :
Tocris
master code :
4382
SKU :
4382/10
product name :
Letrozole
description :
Potent, reversible non-steroidal aromatase inhibitor
target :
Cytochrome P450 Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
285.3
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent, reversible non-steroidal aromatase inhibitor (IC50 = 11.5 nM). Displays antitumor effects in several animal models. Suppresses the endogenous aromatase-induced proliferation of MCF-7 cells.
catalog number base :
4382
product keywords :
CGS20267 non-steroidal aromatase CYP19 inhibitors inhibits potent reversible antitumor antitumour CGS 20267 Cytochrome P450 Estrogen and Related Receptors 4382,
extended description :
Potent, reversible non-steroidal aromatase inhibitor
chemical name text :
4,4 -(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
formula :
C 17 H 11 N 5
formula text :
C17H11N5
cas num :
112809-51-5
2020 USD :
72
2021 USD :
75 USD
alt names :
CGS 20267
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK