BC 11 hydrobromide | Tocris Bioscience 4372/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BC 11 hydrobromide

catalog :

4372/10

quantity :

10 mg (also 50 mg)

price :

207 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Keasey M, Jia C, Pimentel L, Sante R, Lovins C, Hagg T. Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling. J Cell Sci. 2018;131: pubmed publisher
Magnussen S, Hadler Olsen E, Costea D, Berg E, Jacobsen C, Mortensen B, et al. Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - Î²1 (TGF-Î²1) and potential effects on migration and invasion. BMC Cancer. 2017;17:350 pubmed publisher
Semina E, Rubina K, Sysoeva V, Rysenkova K, Klimovich P, Plekhanova O, et al. Urokinase and urokinase receptor participate in regulation of neuronal migration, axon growth and branching. Eur J Cell Biol. 2016;95:295-310 pubmed publisher

image

image 1 :

Cat.No. 4372 - BC 11 hydrobromide C8H11BN2O2S.HBr CAS No. 443776-49-6

product information

brand :

Tocris

master code :

4372

SKU :

4372/10

rank :

0.061

product name :

BC 11 hydrobromide

description :

Selective urokinase (uPA) inhibitor

target :

Urokinase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BC 11 hydrobromide is a selective urokinase (uPA) inhibitor (IC50 = 8.2 M). Exhibits no activity at 8 other related enzymes. Inhibits clot lysis with no effect on clot formation. Also decreases viability of MDA-MB231 breast cancer cells in vitro .

extended description :

Selective urokinase (uPA) inhibitor

chemical name text :

Carbamimidothioic acid (4-boronophenyl)methyl ester hydrobromide

formula :

C 8 H 11 BN 2 O 2 S.HBr

formula text :

C8H11BN2O2S.HBr

cas num :

443776-49-6

USD :

207 USD

product details :

Selective urokinase (uPA) inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage