TC-N 22A | Tocris Bioscience 4370/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-N 22A

catalog :

4370/10

quantity :

10 mg (also 50 mg)

price :

229 USD

citations: 1

Reference
Chiu A, Wang J, Fiske M, Hubálková P, Barse L, Gray J, et al. NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content. Cell Rep. 2019;28:332-341.e5 pubmed publisher

product information

brand :

Tocris

master code :

4370

SKU :

4370/10

product name :

TC-N 22A

target :

Group III mGluR Modulators

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

283.35

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-N 22A is a potent and selective mGlu4 receptor positive allosteric modulator (EC50 = 9 nM in human mGlu4-expressing BHK cells). Selective for mGlu4 over mGlu1, mGlu2, mGlu3, mGlu5 and mGlu7 receptors (EC50 values are 10 M). Brain penetrant.

extended description :

Potent and selective positive allosteric modulator of mGlu4 receptors

chemical name text :

4,5,6,8-Tetrahydro-N-2-pyridinylpyrazolo[3 ,4 :6,7]cyclohepta[1,2]thiazol-2-amine

formula :

C 14 H 13 N 5 S

formula text :

C14H13N5S

cas num :

1314140-00-5

USD :

229 USD

product details :

Potent and selective positive allosteric modulator of mGlu4 receptors

storage :

Store at +4°C