product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Psora 4
catalog :
4367
quantity :
10 mg (also 50 mg)
price :
212 USD
more info or order :
product information
brand :
Tocris
master code :
4367
SKU :
4367/10
product name :
Psora 4
description :
Potent KV1.3 channel blocker
target :
Voltage-gated Potassium Channel Blockers
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
observed molecular weight :
334.37
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent KV1.3 channel blocker (EC50 = 3 nM). Preferentially binds the C-type inactivated state of the channel, similar to the activity of CP 339818 (Cat. No. 1399). Displays 17- to 70-fold selectivity over closely-related KV1 channels (KV1, KV2, KV4 and KV7); exhibits activity at KV1.5 (IC50 = 7.7 nM). Suppresses proliferation of human and rat myelin-specific effector memory T cells (EC50 values are 25 and 60 nM respectively).
catalog number base :
4367
product keywords :
Psora4 Kv1.3 selective ion channels blockers potent KV13 Potassium KV voltage-gated voltage-dependent K+ Voltage-Gated Potassium Channels 4367,
extended description :
Potent KV1.3 channel blocker
chemical name text :
4-(4-Phenylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one
formula :
C 21 H 18 O 4
formula text :
C21H18O4
cas num :
724709-68-6
2020 USD :
205
2021 USD :
212 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK