Lomeguatrib | Tocris Bioscience 4359 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Lomeguatrib

catalog :

4359

quantity :

10 mg (also 50 mg)

price :

240 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4359

SKU :

4359/10

product name :

Lomeguatrib

description :

MGMT inhibitor

target :

Methyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

326.17

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of O 6-methylguanine-DNA methyltransferase (MGMT); (IC50 = 0.009 M in cell-free extracts from HeLa S3 cells); attenuates MGMT activity in vitro and in vivo . Enhances the antitumor activity of temozolomide (Cat. No. 2706) in both human melanoma and MCF-7 xenografts.

catalog number base :

4359

product keywords :

dna mgmt o6-methylguanine-dna methyltransferases inhibitors inhibits psuedosubstrates epigenetics PaTrin-2 DNA Methyltransferases 4359,

extended description :

MGMT inhibitor

chemical name text :

6-[(4-Bromo-2-thienyl)methoxy]-9H-purin-2-amine

formula :

C 10 H 8 BrN 5 OS

formula text :

C10H8BrN5OS

cas num :

192441-08-0

2020 USD :

240

2021 USD :

240 USD

alt names :

PaTrin-2

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage