JHW 007 hydrochloride | Tocris Bioscience 4351/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JHW 007 hydrochloride

catalog :

4351/10

quantity :

10 mg (also 50 mg)

price :

220 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Andersen J, Ringsted K, Bang Andersen B, StrÃ¸mgaard K, Kristensen A. Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter. Sci Rep. 2015;5:15650 pubmed publisher

product information

brand :

Tocris

master code :

4351

SKU :

4351/10

rank :

0.061

product name :

JHW 007 hydrochloride

description :

High affinity dopamine uptake inhibitor

target :

Dopamine Transporter Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JHW 007 hydrochloride is a dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (Ki = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocaine administration in a dose-dependent manner and decreases cocaine and methamphetamine self-administration in rats.

extended description :

High affinity dopamine uptake inhibitor

chemical name text :

(3-endo)-3-[Bis(4-fluorophenyl)methoxy]-8-butyl-8-azabicyclo[3.2.1]octane hydrochloride

formula :

C 24 H 29 F 2 NO.HCl

formula text :

C24H29F2NO.HCl

cas num :

202645-74-7

USD :

220 USD

product details :

High affinity dopamine uptake inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage