Ro 67-7476 | Tocris Bioscience 4346 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ro 67-7476

catalog :

4346

quantity :

10 mg (also 50 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Bariselli S, Tzanoulinou S, Glangetas C, Prévost Solié C, Pucci L, Viguié J, et al. SHANK3 controls maturation of social reward circuits in the VTA. Nat Neurosci. 2016;19:926-934 pubmed publisher

product information

brand :

Tocris

master code :

4346

SKU :

4346/10

product name :

Ro 67-7476

description :

Positive allosteric modulator of mGlu1 receptors

target :

Group I mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

319.39

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Positive allosteric modulator of mGlu1 receptors. Potentiates glutamate-induced calcium release (EC50 = 60.1 nM at rat mGluR1a). Displays no activity at human mGlu1 receptors.

catalog number base :

4346

product keywords :

Ro67-7476 mglur1a positive allosteric modulators pams Glutamate (Metabotropic) Group I Receptors 4346,

extended description :

Positive allosteric modulator of mGlu1 receptors

chemical name text :

(2S)-2-(4-Fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine

formula :

C 17 H 18 FNO 2 S

formula text :

C17H18FNO2S

cas num :

298690-60-5

2020 USD :

205

2021 USD :

212 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage