FH 535 | Tocris Bioscience 4344/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

FH 535

catalog :

4344/10

quantity :

10 mg (also 50 mg)

price :

119 USD

citations: 4

Reference
Skronska Wasek W, Durlanik S, Le H, Schroeder V, Kitt K, Garnett J, et al. The antimicrobial peptide S100A8/A9 produced by airway epithelium functions as a potent and direct regulator of macrophage phenotype and function. Eur Respir J. 2022;59: pubmed publisher
Li H, Yu S, Hao F, Sun X, Zhao J, Xu Q, et al. Insulin-like growth factor binding protein 4 inhibits proliferation of bone marrow mesenchymal stem cells and enhances growth of neurospheres derived from the stem cells. Cell Biochem Funct. 2018;36:331-341 pubmed publisher
Magadum A, Ding Y, He L, Kim T, Vasudevarao M, Long Q, et al. Live cell screening platform identifies PPARÎ´ as a regulator of cardiomyocyte proliferation and cardiac repair. Cell Res. 2017;27:1002-1019 pubmed publisher
Carmona Fontaine C, Deforet M, Akkari L, Thompson C, Joyce J, Xavier J. Metabolic origins of spatial organization in the tumor microenvironment. Proc Natl Acad Sci U S A. 2017;114:2934-2939 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4344

SKU :

4344/10

product name :

FH 535

Description :

Inhibitor of Wnt/ -catenin signaling

target :

beta-Catenin Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

361.2

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

FH 535 is an inhibitor of Wnt/ -catenin signaling and dual antagonist of PPAR / activity. Suppresses -catenin/Tcf-mediated transcription; inhibits -catenin and GRIP1 recruitment to PPAR and . Exhibits antiproliferative effects in transformed colon, lung and liver cancer cell lines.

extended description :

Inhibitor of Wnt/ -catenin signaling

chemical name text :

2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide

formula :

C 13 H 10 Cl 2 N 2 O 4 S

formula text :

C13H10Cl2N2O4S

cas num :

108409-83-2

USD :

119 USD

product details :

Inhibitor of Wnt/ -catenin signaling

storage :

Store at +4°C