UNC 0646 | Tocris Bioscience 4342/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UNC 0646

catalog :

4342/10

quantity :

10 mg (also 50 mg)

price :

263 USD

product information

brand :

Tocris

master code :

4342

SKU :

4342/10

product name :

UNC 0646

description :

Potent and selective G9a and GLP inhibitor

target :

G9a/GLP Inhibitor

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

621.9

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

UNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and GLP, respectively). Potently blocks G9a/GLP methyltransferase activity in cells (IC50 = 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50 = 4.7 M in MCF7 cells). Selective for G9a/GLP over a range of other protein lysine methyltransferases and protein arginine methyltransferases.

extended description :

Potent and selective G9a and GLP inhibitor

chemical name text :

N-(1-Cyclohexyl-4-piperidinyl)-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine

formula :

C 36 H 59 N 7 O 2

formula text :

C36H59N7O2

cas num :

1320288-17-2

USD :

263 USD

product details :

Potent and selective G9a and GLP inhibitor

storage :

Store at +4°C