TAK 779 | Tocris Bioscience 4340/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TAK 779

catalog :

4340/10

quantity :

10 mg (also 50 mg)

price :

218 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4340 - TAK 779 C33H39N2O2.Cl CAS No. 229005-80-5

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4340

SKU :

4340/10

product name :

TAK 779

description :

Potent and selective CCR5 and CCR2 chemokine receptor antagonist

target :

Chemokine Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

531.13

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TAK 779 is a potent and selective CCR5 and CCR2 chemokine receptor antagonist (IC50 values = 1 nM and 27 nM, respectively). TAK 779 blocks the binding of macrophage inflammatory protein 1 and 1 to CHO cells (IC50 = 1 nM) and inhibits replication of R5 HIV-1 at 1.6-3.7 nM. In animal models, TAK 779 protects against ischemic brain injury and prevents development of asthma features.

product keywords :

TAK779 potent selective chemokines receptors antagonists CCR5 CCR2 macrophage viral replication ischemia asthma Chemokine CC Receptors HIV 4340,

extended description :

Potent and selective CCR5 and CCR2 chemokine receptor antagonist

chemical name text :

N-[[4-[[[6,7-Dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl]carbonyl]amino]phenyl]methyl]tetrahydro-N,N-dimethyl-2H-pyran-4-aminium chloride

formula :

C33H39N2O2.Cl

formula text :

C33H39N2O2.Cl

cas num :

229005-80-5

USD :

242

USD 2025 :

218 USD

product details :

Potent and selective CCR5 and CCR2 chemokine receptor antagonist

more info or order :

Tocris Bioscience product webpage