chemical

TG 003

4336/10

10 mg (also 50 mg)

246 USD

4336

4336/10

0.061

TG 003

Potent inhibitor of Clk-family kinases; also inhibits DYRK1A/B

Cdc2-like Kinase Inhibitors

Small Molecules

10 mg (also 50 mg)

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TG 003 is a potent, ATP-competitive inhibitor of Clk-family kinases (IC50 values are 15, 20 and 200 nM for mClk4, 1 and 2 respectively and 10 M for mClk3). Also inhibits DYRK1A/B (IC50 values are 24 and 34 nM respectively). Suppresses serine/arginine-rich protein phosphorylation; affects the regulation of alternative splicing by phosphorylation of SR protein both in vitro and in vivo .

Potent inhibitor of Clk-family kinases; also inhibits DYRK1A/B

(1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone

C 13 H 15 NO 2 S

C13H15NO2S

719277-26-6

246 USD

Potent inhibitor of Clk-family kinases; also inhibits DYRK1A/B

Store the unopened product at 2 - 8 °C. Do not use past expiration date.