AMG 21629 | Tocris Bioscience 4330/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AMG 21629

catalog :

4330/1

quantity :

1 mg

price :

461 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 4330 - AMG 21629 C22H19F3N6O3 CAS No. 939040-79-6

product information

brand :

Tocris

master code :

4330

SKU :

4330/1

rank :

0.061

product name :

AMG 21629

description :

Potent and selective TRPV1 antagonist

target :

TRPV Antagonists

category :

Small Molecules

sizes available :

1 mg

url print :

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details of functionality :

AMG 21629 is a potent and selective TRPV1 antagonist. Blocks Ca2+ uptake by CHO cells expressing TRPV1 receptors (IC50 values are 0.6 and 0.8 nM for capsaicin (Cat. No. 0462) and acid-induced Ca2+ uptake, respectively). Exhibits 4000-fold selectivity for TRPV1 over other TRP channels. Blocks capsaicin-induced flinch response and causes hyperthermia in rats. Orally available and non-CNS penetrant.

extended description :

Potent and selective TRPV1 antagonist

chemical name text :

3-Amino-5-[[2-[(2-methoxyethyl)amino]-6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2(1H)-quinoxalinone

formula :

C 22 H 19 F 3 N 6 O 3

formula text :

C22H19F3N6O3

cas num :

939040-79-6

USD :

461 USD

product details :

Potent and selective TRPV1 antagonist

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage