product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
JW 480
catalog :
4327/10
quantity :
10 mg (also 50 mg)
price :
110 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
4327
SKU :
4327/10
product name :
JW 480
description :
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)
target :
Hydrolase Inhibitors
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at -20°C
observed molecular weight :
333.42
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
JW 480 is a potent and selective inhibitor of the serine hydrolase enzyme KIAA1363 (neutral cholesterol ester hydrolase 1 or NCEH1) (IC50 = 20 nM in mouse brain). JW 480 impairs migration, invasion, survival and tumor growth of prostate cancer cell lines in vivo and reduces monoalkylglycerol ether (MAGE) levels.
product keywords :
KIAA1363 inhibitors inhibits KIAA 1363 prostate cancer AADACL1 MAGE monoalkylglycerol ether JW480 neutral cholesterol ester hydrolase 1 NCEH1 Other Hydrolases 4327,
extended description :
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)
chemical name text :
2-Isopropylphenyl(2-(naphthalen-2-yl)ethyl)carbamate
formula :
C22H23NO2
formula text :
C22H23NO2
cas num :
1354359-53-7
USD :
105
USD 2025 :
110 USD
product details :
Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1)
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK