TC-DAPK 6 | Tocris Bioscience 4301/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC-DAPK 6

catalog :

4301/10

quantity :

10 mg (also 50 mg)

price :

149 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Schmidt M, Caron N, Aly A, Lemarié F, Dal Cengio L, Ko Y, et al. DAPK1 Promotes Extrasynaptic GluN2B Phosphorylation and Striatal Spine Instability in the YAC128 Mouse Model of Huntington Disease. Front Cell Neurosci. 2020;14:590569 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4301

SKU :

4301/10

product name :

TC-DAPK 6

description :

Potent and selective inhibitor of DAPK1

target :

Death-associated Protein Kinase (DAPK) Inhibitors

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

276.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-DAPK 6 is a potent and selective, ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) (IC50 values are 69 and 225 nM for DAPK1 and DAPK3 respectively, when assayed with 10 M ATP). Displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC50 10 M).

product keywords :

TC-DAPK6 death-associated protein kinase dapk1 selective potent inhibitors inhibits 315694-89-4 DAPK 4301, DAPK Inhibitors, DAPK Inhibitor

extended description :

Potent and selective inhibitor of DAPK1

chemical name text :

(4Z)-2-[(E)-2-Phenylethenyl)-4-(3-pyridinylmethylene)-5(4H)-oxazolone

formula :

C17H12N2O2

formula text :

C17H12N2O2

cas num :

2439180-90-0

USD :

147

USD 2025 :

149 USD

product details :

Potent and selective inhibitor of DAPK1

more info or order :

Tocris Bioscience product webpage