VU 0357017 hydrochloride | Tocris Bioscience 4295 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0357017 hydrochloride

catalog :

4295

quantity :

10 mg (also 50 mg)

price :

203 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Jadeja R, Urrunaga N, Ahmad D, Khurana S. Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress. Data Brief. 2016;6:405-9 pubmed publisher

product information

brand :

Tocris

master code :

4295

SKU :

4295/10

product name :

VU 0357017 hydrochloride

description :

Positive allosteric modulator of M1 receptors

target :

mAChR M1 Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

369.89

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 M. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant.

catalog number base :

4295

product keywords :

VU0357017 hydrochloride muscarinics acetylcholine machrs positive allosteric modulators pams m1 selective M1 Receptors 4295,

extended description :

Positive allosteric modulator of M1 receptors

chemical name text :

4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester hydrochloride

formula :

C 18 H 27 N 3 O 3 .HCl

formula text :

C18H27N3O3.HCl

cas num :

1135242-13-5

2020 USD :

195

2021 USD :

203 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage