VU 0357017 hydrochloride | Tocris Bioscience 4295/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0357017 hydrochloride

catalog :

4295/10

quantity :

10 mg (also 50 mg)

price :

236 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Jadeja R, Urrunaga N, Ahmad D, Khurana S. Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress. Data Brief. 2016;6:405-9 pubmed publisher

product information

brand :

Tocris

master code :

4295

SKU :

4295/10

rank :

0.061

product name :

VU 0357017 hydrochloride

description :

Positive allosteric modulator of M1 receptors

target :

mAChR M1 Modulators

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VU 0357017 hydrochloride is a positive allosteric modulator of muscarinic M1 receptors (EC50 = 198 nM). Displays no activity at M2-M5 at concentrations up to 30 M. Potentiates NMDA receptor currents in hippocampal neurons; activity reverses cognitive decifits in a rodent model of hippocampal-dependent memory. CNS penetrant.

extended description :

Positive allosteric modulator of M1 receptors

chemical name text :

4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester hydrochloride

formula :

C 18 H 27 N 3 O 3 .HCl

formula text :

C18H27N3O3.HCl

cas num :

1135242-13-5

USD :

236 USD

product details :

Positive allosteric modulator of M1 receptors

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage