ISO 1 | Tocris Bioscience 4288 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ISO 1

catalog :

4288

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Graham A, Falcone T, Nothnick W. The expression of microRNA-451 in human endometriotic lesions is inversely related to that of macrophage migration inhibitory factor (MIF) and regulates MIF expression and modulation of epithelial cell survival. Hum Reprod. 2015;30:642-52 pubmed publisher

product information

brand :

Tocris

master code :

4288

SKU :

4288/10

product name :

ISO 1

description :

Macrophage migration inhibitory factor (MIF) inhibitor

target :

Cytokine Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

235.24

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Macrophage migration inhibitory factor (MIF) inhibitor (IC50 = 7 M); inhibits MIF tautomerase activity in vitro and in vivo . Protective against mouse models of streptozotocin-induced diabetes mellitus; blocks anti-inflammatory response following LPS exposure and increases survival. Inhibits airway remodeling in a mouse model of chronic asthma. Cell permeable; orally bioavailable.

catalog number base :

4288

product keywords :

ISO1 macrophage migration inhibitory factor antagonists inhibits inhibitors tautomerase MIF Cytokines 4288,

extended description :

Macrophage migration inhibitory factor (MIF) inhibitor

chemical name text :

4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester

formula :

C 12 H 13 NO 4

formula text :

C12H13NO4

cas num :

478336-92-4

2020 USD :

197

2021 USD :

205 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage