Begacestat | Tocris Bioscience 4283/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Begacestat

catalog :

4283/10

quantity :

10 mg (also 50 mg)

price :

212 USD

product information

brand :

Tocris

MasterCode :

4283

SKU :

4283/10

product name :

Begacestat

unit sizes :

10 mg (also 50 mg)

description :

-secretase inhibitor; lowers A 40 and A 42 levels

target :

Secretase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

391.74

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Begacestat is a -secretase inhibitor; selectively inhibits cleavage of amyloid precursor protein (APP) over Notch. Lowers levels of A 42 and A 40 (EC50 values are 12.4 and 14.8 nM respectively in cells expressing human recombinant APP). Orally active.

extended description :

-secretase inhibitor; lowers A 40 and A 42 levels

chemical name text :

5-Chloro-N-[(1S)-3,3,3-trifluoro-1-(hydroxymethyl)-2-(trifluoromethyl)propyl]-2-thiophenesulfonamide

formula :

C 9 H 8 ClF 6 NO 3 S 2

formula text :

C9H8ClF6NO3S2

cas num :

769169-27-9

USD :

212 USD

product details :

-secretase inhibitor; lowers A 40 and A 42 levels

alt names :

GSI-953

storage :

Store at +4°C