Tiagabine hydrochloride | Tocris Bioscience 4256/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Tiagabine hydrochloride

catalog :

4256/10

quantity :

10 mg (also 50 mg)

price :

217 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Sathyanesan A, Kundu S, Abbah J, Gallo V. Neonatal brain injury causes cerebellar learning deficits and Purkinje cell dysfunction. Nat Commun. 2018;9:3235 pubmed publisher

product information

brand :

Tocris

master code :

4256

SKU :

4256/10

rank :

0.061

product name :

Tiagabine hydrochloride

description :

Selective GAT-1 inhibitor; anticonvulsant

target :

GABA Transporter Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Tiagabine hydrochloride is a GABA uptake inhibitor (IC50 = 67 nM in vivo ). Exhibits high affinity and selectivity for the GAT-1 GABA transporter. Anticonvulsant; also attenuates established dynorphin-induced allodynia in a mouse model after systemic administration.

extended description :

Selective GAT-1 inhibitor; anticonvulsant

chemical name text :

(3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid hydrochloride

formula :

C 20 H 25 NO 2 S 2 .HCl

formula text :

C20H25NO2S2.HCl

cas num :

145821-59-6

USD :

217 USD

product details :

Selective GAT-1 inhibitor; anticonvulsant

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage