CID 2858522 | Tocris Bioscience 4246 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CID 2858522

catalog :

4246

quantity :

10 mg

price :

138 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Stec W, Rosiak K, Siejka P, Peciak J, Popęda M, Banaszczyk M, et al. Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes. Oncotarget. 2016;7:31907-25 pubmed publisher

product information

brand :

Tocris

master code :

4246

SKU :

4246/10

product name :

CID 2858522

description :

Selectively inhibits PKC-induced NF- B activation

target :

NFkB/IkB Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

465.63

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selectively inhibits protein kinase C (PKC)-induced activation of the NF- B pathway (IC50 0.1 M for PMA -stimulated IL-8 production). Inhibits antigen receptor-stimulated NF- B activation in chronic lymphocytic leukemia (CLL) B cells. Does not inhibit other NF- B pathways, including that activated by tumor necrosis factor (TNF).

catalog number base :

4246

product keywords :

CID2858522 NF-kB NF-kappaB NF- B inhibitors inhibits PKC protein kinase C-induced activation NF-kB/IkB 4246,

extended description :

Selectively inhibits PKC-induced NF- B activation

chemical name text :

1-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-[2-[(3-hydroxypropyl)amino]-5,6-dimethyl-1H-benzimidazol-1-yl]ethanone

formula :

C 28 H 39 N 3 O 3

formula text :

C28H39N3O3

cas num :

758679-97-9

2020 USD :

135

2021 USD :

138 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage